2025 Summer Intern – investigative PK-ADME (iPK/ADME), Translational Pharmacokinetics and Pharmacodynamics – Development Sciences – Genentech

Title of the Job: 2025 Summer Intern – investigative PK-ADME (iPK/ADME), Translational Pharmacokinetics and Pharmacodynamics – Development Sciences

Location: San Francisco, CA

Job Description: 2025 Summer Intern – Investigative PK-ADME (iPK/ADME), Translational Pharmacokinetics and Pharmacodynamics – Development SciencesDepartment SummaryThis intern position is in the Translational Pharmacokinetics (PK) & Pharmacodynamic (PD) or tPKPD Department within Development Sciences. The tPKPD department applies preclinical models (in vitro, in vivo, and in silico) to determine the pharmacokinetics and/or pharmacodynamics of our biotherapeutics. The iPK/ADME Group focuses its effort on investigating the fate (disposition, biotransformation and distribution) and route of administration of novel biotherapeutic modalities, and effectively influence Drug Design, Delivery and Development Decision; we strive to develop and apply novel technologies through close and extensive collaborations and provide high-quality experimental data to help predict and translating the disposition of biological modalities from animals to humans. The information obtained from this work may be used to help select lead molecules, optimize dosing regimens or understand the PK behavior/metabolic fate of different molecular designs as we help advance molecules through stages of research and into early clinical development.This internship position is located in South San Francisco, on-site.The OpportunityDesign and implement in-vitro studies that are necessary to understand the biodistribution and fate of new modality candidates and predict their behavior in humansInterpret data and communicate results in department meetingsGain knowledge of PK concepts and acquire experience of technology applications in drug developmentWork across disciplines with scientists in a variety of fieldsProgram HighlightsIntensive 12-weeks, full-time (40 hours per week) paid internshipProgram start dates are in May/June (Summer)A stipend, based on location, will be provided to help alleviate costs associated with the internshipOwnership of challenging and impactful business-critical projectsWork with some of the most talented people in the biotechnology industryWho You AreCandidate should be highly motivated individual with a passion for science, a curiosity to solve complex problems, attention to detail, as well as demonstrated effectiveness to work independently and in team settings. The candidate should also be proficient in a broad variety of lab related technical skills (cell culturing, cell base assay, analytical chemistry, etc.). You are expected to have a strong knowledge of basic pharmacology, drug metabolism and PKPD relationships. An individual with strong communication and collaboration skills, along with the ability to clearly articulate solutionsRequired EducationMust have attained a Bachelor’s Degree (not currently enrolled in a graduate program)Must be pursuing a Master’s Degree (enrolled student)Must have attained a Master’s DegreeMust be pursuing a PhD (enrolled student)Required Majors: Pharmacology, Pharmaceutical Science, Biomedical Engineering or related disciplines.Required Skills:Experience of molecular biology assay (3D cell culturing, confocal microscopy etc.), and laboratory skills.Experience with antibodies analytical methods (including HPLC, Western, etc) is preferred.Ability to read and accurately summarize scientific literature.Preferred Knowledge, Skills, and QualificationsExcellent communication, collaboration, and interpersonal skills.Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.Understanding of PK concepts and the use of novel drug delivery system is preferred.Experience with immunohistochemistry, immunofluorescence is nice to have.Previous experience in labeling chemistry, especially with working with radioisotope, is a plus.Relocation benefits are not available for this job posting.The expected salary range for this position based on the primary location of California is $25-$45 hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.#GNE-R&D-Interns-2025Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.

Company Name: Genentech

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